The impact of continuity of care based on information support behavior three-dimensional model on medication adherence and self-management ability of adverse reactions in patients with non-small cell lung cancer undergoing targeted therapy
基于信息-支持-行为三维度模型的延续护理对非小细胞肺癌靶向治疗患者服药依从性及不良反应自我管理能力的影响

摘要

目的 本文分析基于信息-支持-行为（ISB）三维度模型的延续护理对非小细胞肺癌（NSCLC）靶向治疗患者服药依从性和不良反应自我管理能力的影响。方法 本文选取2025年3月至2026年4月期间我院肿瘤内科所收治的42例接受靶向治疗的非小细胞肺癌患者作为研究对象，并使用随机数字表法把这些患者分成观察组和对照组，每组各有21例。对照组进行常规肿瘤专科护理并给予出院指导，观察组在此之上运用ISB三维度模式进行延续护理干预。本文比较两组患者在干预前后服药依从性和不良反应自我管理能力。结果 干预后，观察组Morisky服药依从性量表（MMAS-8）评分显著高于对照组，差异有统计学意义（P<0.05）；观察组不良反应自我管理能力总分显著高于对照组，差异有统计学意义（P<0.05）。结论 运用ISB三维度模型进行延续护理可以提高NSCLC靶向治疗患者的服药依从性，增强患者对不良反应的自我管理能力。临床应推广使用该方法。

Abstract

Objective This article analyzes the impact of continuity of care based on the Information Support Behavior (ISB) three-dimensional model on medication adherence and self-management of adverse reactions in patients with non-small cell lung cancer (NSCLC) undergoing targeted therapy.
Methods This study selected 42 non-small cell lung cancer patients who received targeted therapy in the Department of Oncology of our hospital from March 2025 to April 2026 as the research subjects. These patients were randomly divided into an observation group and a control group using a random number table method, with 21 patients in each group. The control group received routine oncology specialized nursing and discharge guidance, while the observation group continued nursing intervention using the ISB three-dimensional model on top of this. This article compares the medication adherence and self-management ability of adverse reactions between two groups of patients before and after intervention.
Results After the intervention, the Morisky Medication Adherence Scale (MMAS-8) score in the observation group was significantly higher than that in the control group, and the difference was statistically significant (P<0.05); The total score of self-management ability for adverse reactions in the observation group was significantly higher than that in the control group, and the difference was statistically significant (P<0.05).
Conclusion   The use of ISB three-dimensional model for continuous nursing can improve the medication compliance of NSCLC targeted therapy patients and enhance their self-management ability for adverse reactions. This method should be promoted for clinical use.