Comprehensive analysis of the specific impact of intra-abdominal pressure grading on sepsis respiration
全面分析腹内压分级对脓毒血症呼吸的具体影响

摘要

目的 本研究对脓毒血症患者呼吸功能中腹内压分级的作用进行多角度的实证研究与理论分析，分析脓毒血症患者呼吸功能与不同腹内压层级之间的相互作用及其病理生理机制，力求为临床治疗领域提供借鉴资料。方法 2023自2024年度起始之时间分界线秒点，本实验共涉及一百例脓毒血症患者。参照患者腹内压的检测水平分析，本项内容被明确地细分为两个组别：腹内压≥12 mmHg的实验研究受试受检对象组与腹内压<12 mmHg的对照研究受试受检对象组，考虑呼吸节律等关键参数，采用动脉血气与氧合指数等评估手段，对腹内压变动对病人呼吸系统功能的影响进行系统分析。结果 就呼吸频率、血氧饱和度及动脉血气分析结果而言，经数据分析，观察组与对照组差异显著（P值小于0.05），针对呼吸衰竭的发病率、氧合指数（PaO2/FiO2）、动脉血pH值及二氧化碳分压等关键生理参数进行差异分析，与对照组的实验结果相比，观察组的实验表现存在明显差距。结论 脓毒血症患者的呼吸功能与腹内压水平密切相关，分析腹内压值达到或超过12毫米汞柱的脓毒血症患者疾病治疗难点，受检者的肺功能状况出现明显退化，凸显了监测与干预腹内压在脓毒血症患者预后改善中的核心价值。

Abstract

Objective This study conducts empirical research and theoretical analysis on the role of intra-abdominal pressure grading in respiratory function of sepsis patients from multiple perspectives. The interaction between respiratory function and different intra-abdominal pressure levels in sepsis patients and their pathophysiological mechanisms are analyzed, aiming to provide reference materials for clinical treatment.
Methods From 2023 to 2024, a total of 100 sepsis patients were involved in this experiment. Referring to the analysis of the detection level of intra-abdominal pressure in patients, this content is clearly divided into two groups: experimental study subjects with intra-abdominal pressure ≥ 12 mmHg and control study subjects with intra-abdominal pressure<12 mmHg. Considering key parameters such as respiratory rhythm, arterial blood gas and oxygenation index evaluation methods are used to systematically analyze the impact of intra-abdominal pressure changes on the patient's respiratory system function.
Results In terms of respiratory rate, blood oxygen saturation and arterial blood gas analysis results, through data analysis, the difference between the observation group and the control group is significant (P value is less than 0.05). For the incidence rate of respiratory failure, oxygenation index (PaO2/FiO2), arterial blood pH value, partial pressure of carbon dioxide and other key physiological parameters, the experimental performance of the observation group is significantly different from the experimental results of the control group.
Conclusion   The respiratory function of sepsis patients is closely related to the level of intra-abdominal pressure. Analysis of the treatment difficulties of sepsis patients with intra-abdominal pressure of 12 mm Hg or more, the pulmonary function of the examinees has significantly deteriorated, highlighting the monitoring and intervention of intra-abdominal pressure in sepsis. The core value in improving the prognosis of patients with anemia.