Factors influencing negative emotions and nursing intervention strategies for patients with tumor chemotherapy
肿瘤化疗患者负性情绪的影响因素及护理干预策略研究

摘要

目的 探讨肿瘤化疗患者负性情绪的影响因素及护理干预策略。方法 纳入本院化疗肿瘤患者共100例，样本入选时段2025年5月-2025年10月。依照数字随机表法分为2个组别，对照组（n=50）实施常规护理干预，观察组（n=50）评估影响因素，并实施综合护理干预。根据负性情绪、治疗依从性、生活质量评价2组干预效果。结果 干预后，观察组汉密尔顿焦虑量表（HAMA）、汉密尔顿抑郁量表（HAMD）得分较对照组减少（P＜0.05）。干预后，观察组癌症患者生存质量量表（EORTC QLQ-C30）得分相比对照组增加（P＜0.05）。观察组治疗总依从率相比对照组提高（P＜0.05）。结论 根据肿瘤化疗患者负性情绪影响因素实施综合护理干预，能减轻焦虑抑郁心理，提升治疗依从性，改善生活质量。

Abstract

Objective To investigate the factors influencing negative emotions and develop nursing intervention strategies for chemotherapy patients.
Methods A total of 100 chemotherapy patients were enrolled from May to October 2025. Participants were randomly assigned to two groups using a digital randomization table. The control group (n=50) received standard nursing care, while the observation group (n=50) underwent comprehensive nursing interventions targeting identified risk factors. Treatment efficacy was evaluated through three dimensions: negative emotions, treatment adherence, and quality of life.
Results After intervention, the observation group demonstrated significantly lower scores on the Hamilton Anxiety Rating Scale (HAMA) and Hamilton Depression Rating Scale (HAMD) compared to the control group (P<0.05). Additionally, the observation group showed improved scores on the Eastern Oregon Cancer Society Quality of Life in Cancer (EORTC QLQ-C30) scale (P<0.05) and higher overall treatment adherence rates (P<0.05).
Conclusion   Implementing comprehensive nursing interventions based on identified risk factors for negative emotions in chemotherapy patients can effectively alleviate anxiety and depression, enhance treatment adherence, and improve quality of life.