Analysis of high-risk factors and nursing interventions for lupus nephritis patients with renal dysfunction
狼疮性肾炎患者伴肾功能异常的高危因素及护理干预措施分析

摘要

目的 分析狼疮性肾炎患者伴肾功能异常的高危因素，拟定相应的护理干预措施。方法 选取医院2023年5月至2025年5月期间收治的86例狼疮性肾炎患者当作研究对象，依照是否伴有肾功能异常划分为对照组（入选对象的肾功能正常，n=46）、研究组（纳入对象的肾功能异常，n=40）。收集纳入对象的病历资料，分析狼疮性肾炎患者肾功能异常的高危因素。结果 病程时间≥10个月、中重度狼疮活动、并发糖尿病、并发高血压、并发高尿酸血症、并发高三酰甘油血症、并发低蛋白血症、24h尿蛋白≥3.5g是狼疮性肾炎患者肾功能异常的高危因素（P＜0.05）。结论 狼疮性肾炎患者伴肾功能异常的高危因素较多，应尽早识别高危因素并提供相应的护理干预措施，减轻肾损伤程度。

Abstract

Objective To analyze the high-risk factors of renal dysfunction in patients with lupus nephritis and formulate corresponding nursing intervention measures.
Methods A total of 86 patients with lupus nephritis admitted to the hospital from May 2023 to May 2025 were selected as the research objects. They were divided into the control group (with normal renal function, n=46) and the study group (with renal dysfunction, n=40) according to whether they had renal dysfunction. The medical records of the included patients were collected to analyze the high-risk factors of renal dysfunction in patients with lupus nephritis.
Results Disease duration ≥10 months, moderate to severe lupus activity, complicated with diabetes mellitus, complicated with hypertension, complicated with hyperuricemia, complicated with hypertriglyceridemia, complicated with hypoproteinemia, and 24-hour urinary protein ≥3.5g were the high-risk factors for renal dysfunction in patients with lupus nephritis (P<0.05).
Conclusion   There are many high-risk factors for renal dysfunction in patients with lupus nephritis. It is necessary to identify the high-risk factors as early as possible and provide corresponding nursing intervention measures to reduce the degree of renal injury.