Comparison of the effectiveness of low ion polyamine technology and microcolumping method in transfusion testing of hemolytic disease of the newborn and their impact on test satisfaction
低离子凝聚胺技术与微柱凝胶技术在新生儿溶血病新生儿输血检验中的效果对比及对检验满意度的影响

摘要

目的 分析讨论低离子凝聚胺技术（MPT）与微柱凝胶技术（MGT）在新生儿溶血病新生儿输血检验中的效果对比及对检验满意度的影响效果。方法 选择我院2021年3月-2024年3月所接收的已确诊的60例新生儿溶血病新生儿为研究对象，分为观察组（微柱凝胶技术检验）与对照组（低离子凝聚胺技术检验），分别将两组新生儿的血清、放散液与4份同血型的标准红细胞制剂进行交叉配血，比较两种方法学的结果差异与检验满意度。结果 对60例患儿的血清及放散液分别用MPT/MGT 2种方法，与4人份标准红细胞进行交叉配血。患儿血浆与放散液交叉配血采用MPT检测不合次数分别为26次和31次，不合率分别为10.8%和13.1%，采用MGT检测不合次数分别为99次和119次，不合率为41.1%和49.6%，两种方法学交叉配血不合率比较，观察组家属满意情况比对照组高,差异有统计学意义（P<0.05）。结论 新生儿溶血病新生儿输血检验中，微柱凝胶技术交叉配血检测灵敏度更高，结果更为准确，可提高新生儿家属检验满意度，值得广泛推广与应用。

Abstract

Objective To analyze and discuss the effect of low ion polyamine technology (MPT) and microcolumn gel technology (MGT) in the blood transfusion test of newborns with hemolytic disease, and the effect on the satisfaction of the test.
Methods 60 neonates with hemolytic disease of newborn received from 2021.03-2024.03 in our hospital were selected as the research objects, and were divided into the observation group (micro column gel technology test) and the control group (low ion polyamine technology test). The serum and diffusion fluid of the two groups of neonates were cross matched with four standard red blood cell preparations of the same blood type, and the difference of the results of the two methods and the satisfaction of the test were compared.
Results Cross matching of serum and exudate from 60 pediatric patients using MPT/MGT methods with 4 standard red blood cells was performed. The number of times the MPT test for cross matching of the patient's plasma and exudate was 26 and 31, respectively, with a mismatch rate of 10.8% and 13.1%. The number of times the MGT test was 99 and 119, respectively, with a mismatch rate of 41.1% and 49.6%. The comparison of the mismatch rates between the two methods showed that the satisfaction of the observation group's family members was higher than that of the control group, and the difference was statistically significant (P<0.05).
Conclusion   In the blood transfusion test of newborns with hemolytic disease of newborn, the cross matching test of microcolumn gel technology has higher sensitivity and more accurate results, which can improve the satisfaction of newborns' family members, and is worthy of extensive promotion and application.