摘要
目的 分析玻璃酸钠与医用几丁糖关节腔注射分别联合运动干预对膝骨关节炎早中期患者的影响。方法 选择我院2021年1月-2023年12月膝骨关节炎早中期患者为研究对象，一共500例，将其按照注射方式不同分组，分为玻璃酸钠注射联合运动干预，298例，设定为对照组；医用几丁糖关节腔注射联合运动干预，202例，设定为观察组。结果 观察组与对照组治疗后无差异（P＞0.05）。结论 玻璃酸钠与医用几丁糖关节腔注射分别联合运动干预对膝骨关节炎早中期患者影响较明显，均值得推广采纳。
关键词： 玻璃酸钠；医用几丁糖关节腔；运动干预；膝骨关节炎
Abstract
Objective To analyze the effects of joint cavity injection of sodium hyaluronate and medical chitose combined with exercise intervention on patients with early and middle stage of knee osteoarthritis. Methods A total of 500 patients with early and middle stage of knee osteoarthritis in our hospital from January 2021 to December 2023 were selected as the study objects. According to different injection methods, they were divided into sodium hyaluronate injection combined with exercise intervention, 298 cases were set as the control group. Joint injection of medical chitin combined with exercise intervention, 202 cases, set as observation group. Results There was no difference between observation group and control group after treatment (P > 0.05). Conclusion Joint injection of sodium hyaluronate and medical chitose combined with exercise intervention have obvious effects on patients with early and middle stage of knee osteoarthritis, and both are worthy of popularization and adoption.
Key words： Sodium hyaluronate; Medical chitosan joint cavity; Exercise intervention; Knee osteoarthritis
参考文献 References
[1] 陈卫华,庄卫生,黄韶辉.关节腔内PRP注射治疗膝骨关节炎对患者炎症及疼痛因子水平和预后的影响[J].海南医学,2024,35(10):1415-1419.
[2] 张晓贝,李传明.医用几丁糖膝关节内注射联合康复训练治疗中期膝骨关节炎的临床效果[J].临床合理用药,2023,16(32):92-95.
[3] 李志浩,李祥恒,梁祖建.“按揉拔抖”理筋手法对膝骨关节炎患者关节功能及炎症因子的影响[J].广州中医药大学学报,2023,40(11):2833-2838.
[4] 王保森.关节腔玻璃酸钠注射联合中药熏洗治疗膝骨关节炎临床效果观察[J].河南外科学杂志,2023,29(04): 158-160.
[5] 吴远见,张韬,张文君,等.医用几丁糖膝关节内注射联合康复训练对中期膝骨关节炎患者的疗效分析[J].检验医学与临床,2021,18(18):2655-2658+2662.
[6] 邵娜,胡丽波.关节腔内注射医用几丁糖治疗膝骨关节炎的效果分析[J].中国实用医药,2020,15(08):129-131.
[7] 唐新昊,何勇.中药熏洗联合关节腔注射玻璃酸钠治疗轻中度膝骨关节炎的临床研究[J].中医外治杂志,2023, 32(05): 55-57.
[8] 刘金浪,赵家鹏,章友财.揉髌手法联合玻璃酸钠关节腔注射治疗膝骨关节炎30例[J].江西中医药大学学报, 2023, 35(04):37-39.
[9] 钱军,郭琦,王丽,等.中药外敷联合关节腔内注入玻璃酸钠治疗早期膝骨关节炎临床疗效观察[J].山东医药,2024,64(05):82-84.
[10] 张芳,沈华良,沈晶晶,等.超声引导下肩关节腔内注射玻璃酸钠治疗偏瘫肩痛的疗效分析[J].浙江医学,2023, 45(01):72-75+79.