Effect of polyhexamethylene biguanide hydrochloride (PHMB) gauze dressing on type 2 diabetes foot ulcer
聚六亚甲基双胍盐酸盐（PHMB）纱型敷料在2型糖尿病足溃疡中应用效果

摘要

目的 观察分析在2型糖尿病足溃疡患者治疗中使用聚六亚甲基双胍盐酸盐（PHMB）纱型敷料的应用效果和应用价值。方法 采用回顾性研究方法，选择院内就诊的200例2型糖尿病足溃疡患者（样本纳入例数：200例；样本纳入时间：2023年11月到2024年5月），以随机摸球为基础分组方式，分为对照、实验两个小组，观察例数高度一致。分别实施常规敷料，PHMB纱型敷料。收集分析治疗效果。结果 与对照组（常规敷料）相比，实验组（PHMB纱型敷料）治疗后的血糖水平、炎症因子水平更低（P<0.05）；治疗后的溃疡面积更小，疼痛程度更低（P<0.05）。结论 PHMB纱型敷料可以有效促进2型糖尿病足溃疡患者症状改善，缓解疼痛程度，抑制炎症反应，促进恢复，有较高应用价值。

Abstract

Objective To observe and analyze the application effect and value of polyhexamethylene-biguanide hydrochloride (PHMB) yarn dressing in the treatment of patients with type 2 diabetic foot ulcer.
Methods A retrospective study was conducted to select 200 patients with type 2 diabetic foot ulcers (sample number: 200; Sample inclusion time: November 2023 to May 2024) was divided into control and experimental groups based on random ball touching, and the number of observed cases was highly consistent. Conventional dressing and PHMB yarn dressing were respectively applied. The therapeutic effect was collected and analyzed.
Results Compared with the control group (conventional dressing), the levels of blood glucose and inflammatory factors in the experimental group (PHMB gauze dressing) after treatment were lower (P<0.05). The ulcer area after treatment was smaller and the degree of pain was lower (P<0.05).
Conclusion   PHMB gauze dressing can effectively improve the symptoms of patients with type 2 diabetic foot ulcer, relieve pain, inhibit inflammation and promote recovery, and has high application value.