Clinical observation and nursing of hyperbaric oxygen treatment of viral encephalitis
高压氧治疗病毒性脑炎的疗效观察及护理

摘要

目的 探究病毒性脑炎患者执行高压氧治疗的具体效果。方法 2021年3月至2022年5月期间收治的66例病毒性脑炎患者通过双盲法分为对照组、研究组，每组人数33例。对照组实施常规治疗方案，研究组在对照组之上协同开展高压氧治疗。比较两组治疗成效，对比核心症状消失时间及干预前后的相关指标变化，比较并发症发生情况。结果 研究组治疗总有效率为93.94%、并发症发生率为6.06%，优于对照组的治疗总有效率72.73%、并发症发生率24.24%，组间差异P<0.05；研究组在发热、呕吐等核心症状方面的消失时间短于对照组，且血清S100B蛋白、NGF水平及血清氧化应激反应指标优于对照组，差异P<0.05。结论 对病毒性脑炎患者实施高压氧治疗，更利于改善核心症状，提高治疗效果，值得临床借鉴推行。

Abstract

Objective To explore the specific effects of hyperbaric oxygen therapy in patients with viral encephalitis.
Methods From March 2021 to May 2022, 66 patients with viral encephalitis were divided into control group and study group by double-blind method, with 33 cases in each group. The control group received conventional treatment, and the study group received hyperbaric oxygen therapy on top of the control group. The treatment effect of the two groups was compared, the disappearance time of core symptoms and the changes of related indicators before and after intervention were compared, and the incidence of complications was compared.
Results The total effective rate and complication rate of the study group were 93.94% and 6.06%, which were better than that of the control group (72.73% and 24.24%, P<0.05). The disappearance time of core symptoms such as fever and vomiting in the study group was shorter than that in the control group, and the levels of serum S100B protein, NGF and serum oxidative stress response index were better than those in the control group, the difference was P<0.05.
Conclusion   Hyperbaric oxygen therapy for patients with viral encephalitis is more beneficial to improve the core symptoms and improve the therapeutic effect, which is worthy of clinical reference.