摘要
目的 患有急性髓系白血病的患者在接受化疗期间，口腔黏膜可能会发生炎症反应，通过系统性干预护理可以有效降低口腔黏膜炎的发生概率。方法 本次实验选取研究对象100例，研究对象均来自2021年1月~2022年1月，在此期间选取的研究对象均为在我院接受治疗的成人急性髓系白血病患者，将患者按照1:1的形式进行分组，实施不同的护理方式，比较不同护理方式的临床效果差异。结果 （1）对患者的自护能力、抑郁和焦虑情况进行评分，在护理前两组患者的各项评分不存在显著差异（p＞0.05），但是在接受护理后，研究组患者的两项评分改善更加显著（p＜0.05）；（2）比较患者的治疗依从性差异，研究组患者对于护理措施依从性更高，差异显著（p＜0.05）。结论 成人急性髓系白血病患者接受化疗期间，通过系统性护理干预可以有效降低患者口腔黏膜发生炎症反应的概率，提高患者的免疫力，改善患者的心理状态以及自控能力，使得患者对于治疗护理措施更加依从，在临床上值得广泛推广应用。
关键词： 系统性护理干预；成人急性髓系白血病；化疗；口腔黏膜炎
Abstract
Objective Patients with acute myeloid leukemia may have inflammatory reaction in the oral mucosa during chemotherapy. Systematic intervention and nursing can effectively reduce the incidence of oral mucositis. Methods In this experiment, 100 subjects were selected from January 2021 to January 2022. During this period, the selected subjects were adult patients with acute myeloid leukemia who were treated in our hospital. The patients were divided into 1:1 groups, and different nursing methods were implemented to compare the clinical effects of different nursing methods. Results (1) To score the self-care ability, depression and anxiety of patients, there was no significant difference between the two groups before nursing (p>0.05), but after receiving nursing, the two scores of patients in the study group improved more significantly (p<0.05); (2) Compared with the difference of patients' treatment compliance, the patients in the study group had higher compliance with nursing measures, the difference was significant (p<0.05). Conclusion during the chemotherapy period of adult acute myeloid leukemia patients, systematic nursing intervention can effectively reduce the probability of inflammatory reaction of patients' oral mucosa, improve patients' immunity, improve patients' psychological status and self-control ability, and make patients more compliant to treatment and nursing measures. It is worth popularizing and applying in clinic.
Key words： systematic nursing intervention; Adult acute myeloid leukemia; Chemotherapy; Oral mucositis
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