Clinical analysis and nursing observation of patients with relapsed refractory multiple myeloma receivingchimeric antigen receptor T cell immunotherapy
复发难治性弥漫大B细胞淋巴瘤患者行嵌合抗原受体T细胞免疫疗法的临床分析

摘要

目的 探讨嵌合抗原受体T细胞（CAR-T）免疫疗法医治复发难治性弥漫大B细胞淋巴瘤弥漫大B细胞淋巴瘤的护理效果。方法 对2020.4~2021.8于我院行CAR-T治疗的35例弥漫大B细胞淋巴瘤患者进行综合护理干预，观察护理情况。结果 仅有1例患者因自行使用其他药物而无法评估疗效，其他34例患者的总有效率达到100.00%，并发症发生率5.88%，均实现了好转出院。结论 弥漫大B细胞淋巴瘤弥漫大B细胞淋巴瘤患者CAR-T进行CAR-T免疫治疗过程中辅助综合护理干预，效果确切，值得推广。

Abstract

Objective To explore the nursing effect of chimeric antigen receptor T cell (car-t) immunotherapy in the treatment of recurrent refractory multiple myeloma.
Methods: 35 patients with Diffuse large B-cell lymphoma who were treated with car-t in our hospital from April 2020 to August 2021 were given comprehensive nursing intervention, and the nursing situation was observed.
Results: only one patient was unable to evaluate the efficacy due to self use of other drugs. The total effective rate of the other 34 patients reached 100.00%, and the complication rate was 5.88%. All patients were discharged with improvement.
Conclusion  : the comprehensive nursing intervention assisted by car-t in the process of car-t immunotherapy for Diffuse large B-cell lymphoma patients is effective and worthy of promotion.