摘要
目的 对布地奈德联合异丙托溴铵雾化吸入治疗儿童哮喘的临床观察与护理进行探讨。方法 在我院2020年1月-12月之间接收的儿童哮喘患儿的治疗中采用布地奈德和异丙托溴铵雾化吸入治疗方案，并对患儿进行护理干预，观察效果。结果 对照组的治疗有效率显著低于观察组（P<0.05）。两组治疗前各项肺功能指标数据相似（P>0.05），治疗后两组的FVC、FEV1、PEF都有所改善（P<0.05），其中观察组的改善范围更大（P<0.05）。治疗前两组的IL-6、肿瘤坏死因子-α、转化生长因子-β1相差不多（P>0.05），治疗后两组的各项炎性指标都出现不同程度的下降，而下降范围更加明显的是观察组（P<0.05）。结论 哮喘患儿采用布地奈德和异丙托溴铵雾化吸入治疗配合护理干预能够显著改善患者的临床症状和肺功能等指标，治疗有效率高，适合在临床上推广和应用。
关键词： 布地奈德；异丙托溴铵；雾化吸入；儿童哮喘；护理
Abstract
Objective To explore the clinical observation and nursing of budesonide combined with ipratropium bromide inhalation in the treatment of childhood asthma. Methods In the treatment of children with asthma in our hospital from January to December 2020, budesonide and ipratropium bromide atomization inhalation treatment plan was used, and the children were given nursing intervention to observe the effect. Results The treatment effective rate of the control group was significantly lower than that of the observation group (P<0.05). The data of various pulmonary function indicators in the two groups before treatment were similar (P>0.05). After treatment, the FVC, FEV1, and PEF of the two groups were improved (P<0.05), and the improvement range in the observation group was larger (P<0.05). . Before treatment, the IL-6, tumor necrosis factor-α and transforming growth factor-β1 of the two groups were similar (P>0.05). is the observation group (P<0.05). Conclusion The use of budesonide and ipratropium bromide atomization inhalation therapy combined with nursing intervention in children with asthma can significantly improve the patients' clinical symptoms and pulmonary function and other indicators, and the treatment efficiency is high, which is suitable for clinical promotion and application.
Key words： budesonide; ipratropium bromide; nebulized inhalation; childhood asthma; nursing
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